Multiple Sclerosis Care in the Hospital Setting: Novel Neuroimaging Techniques, Individualized Treatment Strategies, and Management of Comorbidities

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Release Date: March 23, 2018
Expiration Date: March 23, 2019

Early diagnosis in MS is imperative to minimize progression and improve patient quality of life. However, many patients with MS continue to receive delated diagnoses. In addition, a lack of coordination within the multidisciplinary management team can lead to inadequate management of MS-associated comorbidities.

In order to help ensure accurate and timely diagnoses and improve care-team coordination, Multiple Sclerosis Care in the Hospital Setting will explore the most recent advances in evidence-based diagnosis (including the use of biomarkers and neuroimaging), methods to individualize management with current and emerging therapies, strategies to address nonadherence, and the use of the whole-body approach in MS management.

Welcome and Introductions
Diagnostic Guidelines
Wellness Approach and Coordination of Care
Evidence-based Treatment for the Four Types of MS
Concluding Remarks


Professor and Vice Chair (Clinical Affairs)
 Department of Neurology
 Director, MS Comprehensive Care Center
 Stony Brook University Medical Center
 Stony Brook, NY



Patricia Coyle, MD, FAAN, FANA is a Professor and Vice Chair (Clinical Affairs) of Neurology and Director of the Multiple Sclerosis Comprehensive Care Center at Stony Brook University Medical Center in Stony Brook, NY. She received a BS degree with highest honors from Fordham University and her medical doctorate from the Johns Hopkins School of Medicine, where she was elected to Alpha Omega Alpha. While at the Johns Hopkins School of Medicine, she completed a residency and chief residency in neurology, followed by a two-year fellowship in neuroimmunology and neurovirology. She then went on to establish a successful research laboratory in addition to building a busy clinical practice at the Stony Brook University Medical Center. 

Dr. Coyle is the author of numerous articles on clinical and basic research aspects of multiple sclerosis (MS) and neurologic infections and she is recognized as a leading expert in these areas. Her other areas of expertise include Lyme disease and neurologic infections, cerebrospinal fluid, therapeutics, and neuroimmunology. Her research has been supported by the National Institutes of Health and other organizations. She is currently involved in a number of therapeutic trials testing new immunotherapies for MS, as well as studies addressing neurologic aspects of Lyme disease.

In addition to her busy clinical and research careers, she has held active leadership positions in a number of national and international organizations and academic societies, including the American Academy of Neurology, American Neurological Association, National MS Society, and the American Board of Psychiatry and Neurology. She lectures widely on MS and neurologic infections to national and international audiences.

Director, MS Center
 Co-chief, MS Section
 Associate Professor of Neurology
 Perelman School of Medicine
 University of Pennsylvania
 Philadelphia, PA


Clyde Markowitz, MD is Director of the MS Center at the Hospital of the University of Pennsylvania. and an Associate Professor of Neurology at the Perelman School of Medicine at University of Pennsylvania in Philadelphia. He earned his medical doctorate from the Columbia University College of Physicians and Surgeons. He also completed residency, postdoctoral research, and clinical fellowship studies at the Neurological Institute at Columbia University College of Physicians and Surgeons in New York.

Dr. Markowitz’s expertise is in the field of MS and he is involved with many clinical trials developing new compounds for the treatment of MS. His research interests include utilization of new MRI techniques to study the pathogenesis of MS, vision outcome measures in MS, and the immunology of MS. He has held the position of Chairman of the Clinical Advisory Committee for the Delaware Valley Chapter of the National Multiple Sclerosis Society.

Dr. Markowitz is the author or co-author of a number of publications, and he serves as an ad hoc reviewer for Multiple Sclerosis, Annals of Neurology. Archives of Neurology, Journal of the Neurological Sciences, Neuro-Rehabilitation, Neural Repair, Journal of Clinical Immunology, and The Consultant. He is a member of the American Academy of Neurology and is certified by the National Board of Medical Examiners and the American Board of Psychiatry and Neurology. His work has been published several times in journals, such as Annals of Neurology and Neurology

This activity is intended for MS specialists, neurologists, PCPs, and other healthcare professionals who manage patients with MS.

This program is designed to address the following IOM competencies: provide patient-centered care and employ evidence-based practice.                                                           

At the conclusion of this activity, participants should be able to demonstrate the ability to:

  • Implement strategies to improve the differential diagnosis of MS, as well as to assess treatment response, including use of neuroimaging techniques and biomarkers
  • Describe the evidence-based strategies for individualizing treatment in MS, including emerging treatments for progressive MS
  • Utilize a wellness approach to MS care to improve adherence to medications and lifestyle measures, as well as to improve care coordination for comorbidities

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Potomac Center for Medical Education and Rockpointe. The Potomac Center for Medical Education is accredited by the ACCME to provide continuing medical education for physicians.

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The Potomac Center for Medical Education designates this live activity for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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All persons in a position to control the content of a continuing medical education program provided by PCME are required to disclose any relevant financial relationships with any commercial interest to PCME as well as to learners. All conflicts of interest are identified and resolved by PCME in accordance with the Standards for Commercial Support in advance of delivery of the activity to learners. Disclosures will be made known to the participants prior to the activity.

The content of this activity was vetted by an external reviewer to assure objectivity and that the activity is free of commercial bias.

Program Faculty Disclosures
The program faculty reported the following relevant financial relationships that they or their spouse/partner have with commercial interests:  

Patricia Coyle, MD, FAAN, FANA: Consultant: Accordant, Acorda, Bayer, Biogen, Celgene, Genentech/Roche, Genzyme/Sanofi, Novartis, Serono, Teva; Research: Actelion, Alkermes, Genentech/Roche, MedDay, Novartis, Opexa

Clyde Markowitz, MD: Consultant: Bayer, Biogen, Celgene, Genentech/Roche, Novartis, Sanofi Genzyme, Serono, Teva; Research: Actelion, Genentech/Roche, Novartis                                                                                          

Non-faculty Content Contributors Disclosures
Non-faculty content contributors and/or reviewers reported the following relevant financial relationships that they or their spouse/partner have with commercial interests:

Chad Williamson, MS, MBA, CMPP; Blair St. Amand; Lindsay Scott, PT, DPT, ATC: Nothing to disclose

Joe Chebli, PharmD: Spouse is an Employee and Stock/Shareholder of: Bristol-Myers Squibb

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There is no fee for this activity. To receive credit, participants must take the pre-test, view this CME activity in its entirety, and then complete the post-test, with a score of 70% or better, and evaluation. The estimated time for completion of this activity is 1 hour. To receive their certificates, participants must demonstrate mastery of the presented material via the post-test.  Participant is allowed to take the post-test multiple times.

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Jointly provided by Potomac Center for Medical Education and Rockpointe


This activity is supported by educational grants from Novartis Pharmaceuticals Corporation and Sanofi Genzyme.